Biologically relevant small variations of intra-cellular pH can have significant effect on stability of protein–DNA complexes, including the nucleosome
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DOI: 10.3389/fmolb.2023.1067787
Abstract: Stability of a protein-ligand complex may be sensitive to pH of its environment. Here we explore, computationally, stability of a set of protein-nucleic acid complexes using fundamental thermodynamic linkage relationship. The nucleosome, as well as… read more here.
Keywords: stability protein; dna; intra nuclear; intra cellular ... See more keywords