Differential Regulation of Cardiac Function and Intracardiac Cytokines by Rapamycin in Healthy and Diabetic Rats
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DOI: 10.1155/2017/5724046
Abstract: Diabetes is comorbid with cardiovascular disease and impaired immunity. Rapamycin improves cardiac functions and extends lifespan by inhibiting the mechanistic target of rapamycin complex 1 (mTORC1). However, in diabetic murine models, Rapamycin elevates hyperglycemia and… read more here.
Keywords: cytokines rapamycin; intracardiac cytokines; cardiac function; differential regulation ... See more keywords