Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models
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DOI: 10.1080/2162402x.2022.2147317
Abstract: ABSTRACT Previous studies have shown that local delivery of tumor antigen-specific CD8+ T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious. Peritoneal dissemination of cancer is a frequent and often fatal patient… read more here.
Keywords: specific cd8; tumor; intracavitary adoptive; adoptive transfer ... See more keywords