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Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20102375
Abstract: Dysregulation of cellular energy metabolism is closely linked to cancer development and progression. Calorie or glucose restriction (CR or GR) inhibits energy-dependent pathways, including IGF-1/PI3K/Akt/mTOR, in cancer cells. However, alterations in proton dynamics and reversal…
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Keywords:
restriction inhibits;
treatment;
intracellular alkalinization;
glucose restriction ... See more keywords