Selection and Use of Intracellular Antibodies.
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DOI: 10.1007/978-1-4939-8648-4_25
Abstract: Intracellularly expressed recombinant antibodies, or intrabodies, are powerful tools for cell biology studies as well as therapeutic applications. Cell biologists use them to either block the intracellular antibody target or to image endogenous target dynamics.… read more here.
Keywords: selection use; intracellular antibodies; biology; use intracellular ... See more keywords
Intracellular Antibodies for Drug Discovery and as Drugs of the Future
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DOI: 10.3390/antib12010024
Abstract: The application of antibodies in cells was first shown in the early 1990s, and subsequently, the field of intracellular antibodies has expanded to encompass antibody fragments and their use in target validation and as engineered… read more here.
Keywords: drug discovery; antibodies drug; discovery drugs; drug ... See more keywords