New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-57732-6_13
Abstract: Transient receptor potential canonical (TRPC) proteins were identified as molecular candidates of receptor- and/or store-operated channels because of their close homology to the Drosophila TRP and TRPL. Functional studies have revealed that TRPC channels play… read more here.
Keywords: trpc proteins; trpc; ca2; intracellular ca2 ... See more keywords
TRPC Channels and Brain Inflammation.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1088-4_10
Abstract: Nonresolving low-grade inflammation is supposed to underly the basis of chronic disorders including cardiovascular diseases, cancer, diabetes, obesity, and psychiatric disorders such as depression and Alzheimer's diseases. There is increasing evidence suggesting that pathophysiology of… read more here.
Keywords: channels brain; trpc channels; psychiatric disorders; inflammation ... See more keywords
Ischemia deteriorates spike encoding at cortical GABAergic neurons and cerebellar Purkinje cells by increasing the intracellular Ca2+
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2017.03.005
Abstract: GABAergic neurons play a critical role in the central nervous system, such as well-organized behaviors. The ischemic cell death is presumably initiated by neuronal excitotoxicity resulted from the dysfunction of GABAergic neurons. It is not… read more here.
Keywords: cortical gabaergic; ischemia; intracellular ca2; spike encoding ... See more keywords
Oxytocin induces intracellular Ca2+ release in cardiac fibroblasts from neonatal rats.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2019.102099
Abstract: Pituitary neuropeptide oxytocin is increasingly recognised as a cardiovascular hormone, in addition to its many regulatory roles in other organ systems. Studies in atrial and ventricular myocytes from the neonatal and adult rats have identified… read more here.
Keywords: oxytocin induces; oxytocin; cardiac fibroblasts; intracellular ca2 ... See more keywords
JPT2: The missing link between intracellular Ca2+ release channels and NAADP?
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102405
Abstract: NAADP (nicotinic acid adenine dinucleotide phosphate) is a potent second messenger releasing Ca2+ from endolysosomes through two-pore channels (TPCs) and from the endoplasmic reticulum (ER) through type 1 ryanodine receptors (RyR1). How NAADP activates these… read more here.
Keywords: link intracellular; link; ca2 release; jpt2 missing ... See more keywords
(‐)‐Terpinen‐4‐ol changes intracellular Ca2+ handling and induces pacing disturbance in rat hearts
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.04.022
Abstract: Abstract (‐)‐Terpinen‐4‐ol is a naturally occurring plant monoterpene and has been shown to have a plethora of biological activities. The objective of this study was to investigate the effects of (‐)‐terpinen‐4‐ol on the rat heart,… read more here.
Keywords: terpinen; ca2 handling; effect; ca2 ... See more keywords
Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.07.012
Abstract: Aberrations in intracellular calcium (Ca2+) have been well established within amyotrophic lateral sclerosis (ALS), a severe motor neuron disease. Intracellular Ca2+ concentration is controlled in part through the endoplasmic reticulum (ER) mitochondria Ca2+ cycle (ERMCC).… read more here.
Keywords: intracellular calcium; ca2; sigma receptor; activation ... See more keywords
Antiproliferative effect of a benzofuran derivate based on the structure of amiodarone on Leishmania donovani affecting mitochondria, acidocalcisomes and intracellular Ca2+ homeostasis.
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology international"
DOI: 10.1016/j.parint.2019.02.006
Abstract: Leishmaniasis is a parasitic disease representing an important problem of public health. Visceral leishmaniasis, resulting from infection with Leishmania donovani, causes considerable mortality and morbidity in the poorest region of the word. At present there… read more here.
Keywords: intracellular ca2; leishmania donovani; ca2 homeostasis; ca2 ... See more keywords
A new approach for ratiometric in vivo calcium imaging of microglia
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DOI: 10.1038/s41598-017-05952-3
Abstract: Microglia, resident immune cells of the brain, react to the presence of pathogens/danger signals with a large repertoire of functional responses including morphological changes, proliferation, chemotaxis, production/release of cytokines, and phagocytosis. In vitro studies suggest… read more here.
Keywords: vivo; state intracellular; steady state; ca2 ... See more keywords
Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Stem cells and development"
DOI: 10.1089/scd.2017.0114
Abstract: Stromal cell-derived factor-1α (SDF-1α) drives endothelial colony-forming cell (ECFC) homing and incorporation within neovessels, thereby restoring tissue perfusion in ischemic tissues and favoring tumor vascularization and metastasis. SDF-1α stimulates ECFC migration by activating the Gi-protein-coupled… read more here.
Keywords: kinase; migration; ca2; intracellular ca2 ... See more keywords
Plastin 1 promotes osteoblast differentiation by regulating intracellular Ca2.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmaa027
Abstract: Osteoblast differentiation is a key process in bone homeostasis. Mutations in plastin 3 have been reported to be responsible for X-linked osteoporosis. Plastin 3 and plastin 2 act synergistically to regulate osteoblast differentiation. However, the… read more here.
Keywords: promotes osteoblast; differentiation; osteoblast differentiation; intracellular ca2 ... See more keywords