Monitoring Intracellular Calcium in Response to GPCR Activation: Comparison Between Microtiter Plates and Microfluidic Assays.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1221-7_19
Abstract: Microfluidic strategies combined with transduction and electronic integration have the promise of enabling miniaturized, combinatorial assays at higher speeds and lower costs, while at the same time mimicking the local chemical concentrations and force fields… read more here.
Keywords: intracellular calcium; response; monitoring intracellular; calcium response ... See more keywords
The intracellular calcium dynamics in a single vascular endothelial cell being squeezed through a narrow microfluidic channel
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-020-01368-7
Abstract: Revealing the mechanisms underlying the intracellular calcium responses in vascular endothelial cells (VECs) induced by mechanical stimuli contributes to a better understanding for vascular diseases, including hypertension, atherosclerosis, and aneurysm. Combining with experimental measurement and… read more here.
Keywords: intracellular calcium; vascular endothelial; narrow microfluidic; squeezed narrow ... See more keywords
Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-3983-3
Abstract: A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices. In contrast, the drug exerted no significant effect on intracellular calcium… read more here.
Keywords: intracellular calcium; rat hippocampal; hippocampal slices; calcium ... See more keywords
Memantine Can Reduce Ethanol-Induced Caspase-3 Activity and Apoptosis in H4 Cells by Decreasing Intracellular Calcium
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0948-3
Abstract: Caspase-3 activation and apoptosis are associated with various neurodegenerative disorders. Calcium activation is an important factor in promoting apoptosis. We, therefore, assessed the role of intracellular calcium in ethanol-induced activation of caspase-3 in H4 human… read more here.
Keywords: ethanol induced; caspase; intracellular calcium; apoptosis ... See more keywords
Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.07.015
Abstract: Cold atmospheric-pressure plasma (CAP) has been emerging as a promising tool for cancer therapy in recent times. In this study, we used a CAP device with nitrogen gas (N2CAP) and investigated the effect of the… read more here.
Keywords: nitrogen; intracellular calcium; cell death;
Importance of Altered Levels of SERCA, IP3R, and RyR in Vascular Smooth Muscle Cell.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2016.11.3206
Abstract: Calcium cycling between the sarcoplasmic reticulum (SR) and the cytosol via the sarco-/endoplasmic reticulum Ca-ATPase (SERCA) pump, inositol-1,4,5-triphosphate receptor (IP3R), and Ryanodine receptor (RyR), plays a major role in agonist-induced intracellular calcium ([Ca2+]cyt) dynamics in… read more here.
Keywords: intracellular calcium; serca ip3r; levels serca; ip3r ryr ... See more keywords
Intracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.04.013
Abstract: Graded Shh signaling across fields of precursor cells coordinates patterns of gene expression, differentiation, and morphogenetic behavior as precursors form complex structures, such as the nervous system, the limbs, and craniofacial skeleton. Here we discover… read more here.
Keywords: mobilization required; intracellular calcium; calcium mobilization; shh dependent ... See more keywords
Dystrophin gene expression and intracellular calcium changes in the giant freshwater prawn, Macrobrachium rosenbergii, in response to white spot symptom disease infection
Sign Up to like & getrecommendations! Published in 2017 at "Heliyon"
DOI: 10.1016/j.heliyon.2017.e00446
Abstract: Background Dystrophin, an essential protein functional in the maintenance of muscle structural integrity is known to be responsible for muscle deterioration during white spot syndrome virus (WSSV) infection among prawn species. Previous studies have shown… read more here.
Keywords: intracellular calcium; white spot; muscle; infection ... See more keywords
Trop2 inhibition of P16 expression and the cell cycle promotes intracellular calcium release in OSCC.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.07.234
Abstract: Trop2 is an intracellular calcium signal transducer and a prognostic biomarker in many cancers. P16 is a cell cycle gene that negatively regulates cell proliferation and division in most human cancers. Oral squamous cell carcinoma… read more here.
Keywords: cell; expression; intracellular calcium; cell cycle ... See more keywords
Circulating IgGs in Type 2 Diabetes with Atrial Fibrillation Induce IP3-Mediated Calcium Elevation in Cardiomyocytes
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DOI: 10.1016/j.isci.2020.101036
Abstract: Summary Higher risk of cardiac arrhythmias including atrial fibrillation (AF) associates with type 2 diabetes mellitus (T2DM) with the underlying mechanism largely unknown. The present study reported a subset of circulating immunoglobulin G autoantibodies (IgGs)… read more here.
Keywords: atrial fibrillation; intracellular calcium; type diabetes; elevation ... See more keywords
Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys
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DOI: 10.1016/j.isci.2021.102528
Abstract: Summary Growing evidence suggests that renal purinergic signaling undergoes significant remodeling during pathophysiological conditions such as diabetes. This study examined the renal P2 receptor profile and ATP-mediated calcium response from podocytes in glomeruli from kidneys… read more here.
Keywords: receptor; intracellular calcium; purinergic receptor; atp mediated ... See more keywords