GPCRs in Intracellular Compartments: New Targets for Drug Discovery
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101343
Abstract: The architecture of eukaryotic cells is defined by extensive membrane-delimited compartments, which entails separate metabolic processes that would otherwise interfere with each other, leading to functional differences between cells. G protein-coupled receptors (GPCRs) are the… read more here.
Keywords: gpcrs intracellular; cell; new targets; targets drug ... See more keywords
The Distribution and Role of the CFTR Protein in the Intracellular Compartments
Sign Up to like & getrecommendations! Published in 2021 at "Membranes"
DOI: 10.3390/membranes11110804
Abstract: Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is caused by mutations in the gene encoding CFTR with the most common phenylalanine deletion at position 508. CFTR is an… read more here.
Keywords: cftr; intracellular compartments; distribution role; role cftr ... See more keywords