Hyaluronic Acid-Based pH-Sensitive Polymer-Modified Liposomes for Cell-Specific Intracellular Drug Delivery Systems.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00551
Abstract: For the enhancement of therapeutic effects and reduction of side effects derived from anticancer drugs in cancer chemotherapy, it is imperative to develop drug delivery systems with cancer-specificity and controlled release function inside cancer cells.… read more here.
Keywords: drug delivery; modified liposomes; delivery systems; intracellular drug ... See more keywords
Potential-Independent Intracellular Drug Delivery and Mitochondrial Targeting.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c09456
Abstract: In this study, two types of the fluoroamphiphile analogs were synthesized and self-assembled into the "core-shell" micellar nanocarriers for intracellular delivery and organelle targeting. Using the fluorescent dyes or vitamin E succinate as the cargo,… read more here.
Keywords: potential independent; mitochondrial targeting; drug delivery; intracellular drug ... See more keywords
SERS Endoscopy for Monitoring Intracellular Drug Dynamics.
Sign Up to like & getrecommendations! Published in 2023 at "ACS sensors"
DOI: 10.1021/acssensors.3c00394
Abstract: Understanding the dynamics and distribution of medicinal drugs in living cells is essential for the design and discovery of treatments. The tools available for revealing this information are, however, extremely limited. Here, we report the… read more here.
Keywords: drug dynamics; endoscopy monitoring; intracellular drug; monitoring intracellular ... See more keywords
An intracellular drug reservoir
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Microbiology"
DOI: 10.1038/s41579-019-0241-2
Abstract: This study reports that lipid droplets provide a reservoir for a lipophilic tuberculosis drug and enhance drug efficacy. read more here.
Keywords: drug; microbiology; drug reservoir; intracellular drug ... See more keywords
A pH and reduction dual-sensitive polymeric nanomicelle for tumor microenvironment triggered cellular uptake and controlled intracellular drug release.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00825j
Abstract: Minimal drug leakage during blood circulation and intracellular drug delivery in tumor sites are of great significance in chemotherapeutics. Herein we propose an interlayer crosslinked polymeric micelle with tumor acidity and reduction dual sensitivity for… read more here.
Keywords: drug; dual sensitive; reduction dual; intracellular drug ... See more keywords
Hybrid micelles enhance tumour therapy by remodelling biodistribution and improving intracellular drug release.
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DOI: 10.1039/d1bm01158h
Abstract: PEGylated micelles have been widely used for tumour therapy. Although PEGylation can prolong the blood circulation time, there is only less than 5% of administered micelles that can be transported to tumour sites and over… read more here.
Keywords: hybrid micelles; drug release; intracellular drug; tumour therapy ... See more keywords
ATP Aptamer-Modified Quantum Dots with Reduced Glutathione/Adenosine Triphosphate Dual Response Features as a Potential Probe for Intracellular Drug Delivery Monitoring of Vesicular Nanocarriers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2019.2694
Abstract: Nanoparticles have great promise in drug delivery, but their functional mechanisms are very complicated. Monitoring the payloads or carriers by conventional labeling strategies may result in an inaccurate perception of the effectiveness of nano drug… read more here.
Keywords: modified quantum; probe; drug delivery; drug ... See more keywords