The Intracellular and Extracellular Microenvironment of Tumor Site: The Trigger of Stimuli-Responsive Drug Delivery Systems.
Sign Up to like & getrecommendations! Published in 2022 at "Small methods"
DOI: 10.1002/smtd.202101437
Abstract: The tumor microenvironment (TME), including intracellular and extracellular microenvironment, contains many biochemical indicators (such as acidity/alkalinity, oxygen content, and enzymatic activity) that are different from the normal physiological environment. These abnormal biochemical indicators can accelerate… read more here.
Keywords: microenvironment; intracellular extracellular; drug delivery; extracellular microenvironment ... See more keywords
Intracellular and extracellular TGF-β signaling in cancer: some recent topics
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers of Medicine"
DOI: 10.1007/s11684-018-0646-8
Abstract: Transforming growth factor (TGF)-β regulates a wide variety of cellular responses, including cell growth arrest, apoptosis, cell differentiation, motility, invasion, extracellular matrix production, tissue fibrosis, angiogenesis, and immune function. Although tumor-suppressive roles of TGF-β have… read more here.
Keywords: extracellular tgf; tgf; cancer; intracellular extracellular ... See more keywords
Endolysosome and Autolysosome Dysfunction in Alzheimer’s Disease: Where Intracellular and Extracellular Meet
Sign Up to like & getrecommendations! Published in 2019 at "CNS Drugs"
DOI: 10.1007/s40263-019-00643-1
Abstract: Disturbed proteostasis as reflected by a massive accumulation of misfolded protein aggregates is a central feature in Alzheimer’s disease. Proteostatic disturbances may be caused by a shift in protein production and clearance. Whereas rare genetic… read more here.
Keywords: endolysosome autolysosome; alzheimer disease; dysfunction; disease ... See more keywords
The dual face of NAMPT: Intracellular/extracellular protein and diagnostic/therapeutic target in cancer
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.103109
Abstract: Since the discovery of nicotinamide phosphoribosyltransferase (NAMPT) as a pre-B cell-enhancing factor in 1994 by Samal et al. [1], many papers have described the pleiotropic function of this enzyme. A vital role of NAMPT in… read more here.
Keywords: nampt intracellular; dual face; face nampt; target ... See more keywords
The autofluorescence characteristics of bacterial intracellular and extracellular substances during the operation of anammox reactor
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DOI: 10.1038/srep39289
Abstract: Anammox is a cost-effective process to treat nitrogenous wastewater. In this work, excitation–emission matrix (EEM) fluorescence spectroscopy was used to characterize the intracellular and extracellular substances of anammox sludge during reactor operation of 276 days.… read more here.
Keywords: extracellular substances; like peaks; operation; protein like ... See more keywords
Bacteria engineered with intracellular and extracellular nanomaterials for hierarchical modulation of antitumor immune responses.
Sign Up to like & getrecommendations! Published in 2023 at "Materials horizons"
DOI: 10.1039/d3mh00249g
Abstract: Induction of immunogenic cell death (ICD) by hyperthermia can initiate adaptive immune responses, emerging as an attractive strategy for tumor immunotherapy. However, ICD can induce proinflammatory factor interferon-γ (IFN-γ) production, leading to indoleamine 2,3-dioxygenase 1… read more here.
Keywords: immune responses; bacteria engineered; intracellular extracellular; cusvnp20009nb ... See more keywords
Rifabutin Is Bactericidal against Intracellular and Extracellular Forms of Mycobacterium abscessus
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00363-20
Abstract: Mycobacterium abscessus is increasingly recognized as an emerging opportunistic pathogen causing severe lung diseases. As it is intrinsically resistant to most conventional antibiotics, there is an unmet medical need for effective treatments. Repurposing of clinically… read more here.
Keywords: rfb; mycobacterium abscessus; abscessus; intracellular extracellular ... See more keywords
ASO Author Reflections: Involvement of Intracellular and Extracellular High-Mobility Group Box-1 in the Progression of Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-08415-8
Abstract: Although high-mobility group box-1 (HMGB1) was originally known as a nuclear protein, it also acts as an extracellular protein and proinflammatory cytokine. Furthermore, recent evidence demonstrated that both intracellular and extracellular HMGB1 contribute to carcinogenesis,… read more here.
Keywords: hmgb1; high mobility; group box; intracellular extracellular ... See more keywords
Alpha-synuclein at the intracellular and the extracellular side: functional and dysfunctional implications
Sign Up to like & getrecommendations! Published in 2017 at "Biological Chemistry"
DOI: 10.1515/hsz-2016-0201
Abstract: Abstract Alpha-synuclein (α-syn) is an abundant neuronal protein whose physiological function, even if still not completely understood, has been consistently related to synaptic function and vesicle trafficking. A group of disorders known as synucleinopathies, among… read more here.
Keywords: side functional; syn; extracellular side; synuclein intracellular ... See more keywords
Clinical and Functional Significance of Intracellular and Extracellular microRNA-25-3p in Osteosarcoma.
Sign Up to like & getrecommendations! Published in 2018 at "Acta medica Okayama"
DOI: 10.18926/amo/55857
Abstract: Although there is considerable evidence indicating that the dysregulation of microRNAs (miRNAs) in malignant tumors plays a role in tumor development, the overall function of miRNAs and their clinicopathological significance are not well understood. In… read more here.
Keywords: functional significance; extracellular microrna; significance intracellular; clinical functional ... See more keywords
Metabolic Pathway Profiling in Intracellular and Extracellular Environments of Streptococcus thermophilus During pH-Controlled Batch Fermentations
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.03144
Abstract: Elucidating the metabolite profiles during the growth of Streptococcus thermophilus is beneficial for understanding its growth characteristics. The changes in the intracellular and extracellular concentrations of carbohydrates, nucleotides, amino sugars, nucleoside sugars, fatty acids, and… read more here.
Keywords: metabolic pathway; profiling intracellular; extracellular environments; streptococcus thermophilus ... See more keywords