Chemically Tuned Intracellular Gene Delivery by Core-Shell Nanoparticles: Effects of Proton Buffering, Acid Degradability, and Membrane Disruption
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202100718
Abstract: Nanoparticles consisting of a condensed nucleic acid core surrounded by protective layers which aid to overcome extracellular and intracellular hurdles to gene delivery (i. e., core‐shell nanoparticles, CSNPs) synthetically mimic viruses. The outer shells shield the… read more here.
Keywords: core; intracellular gene; gene delivery; gene ... See more keywords
Pangenome-based trajectories of intracellular gene transfers in Poaceae unveil high cumulation in Triticeae.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad319
Abstract: Intracellular gene transfers (IGTs) between the nucleus and organelles, including plastids and mitochondria, constantly reshape the nuclear genome during evolution. Despite the substantial contribution of IGTs to genome variation, the dynamic trajectories of IGTs at… read more here.
Keywords: trajectories intracellular; gene transfers; intracellular gene; pangenome based ... See more keywords