Facile Transformation of Murine and Human Primary Dendritic Cells into Robust and Modular Artificial Antigen-Presenting Systems by Intracellular Hydrogelation.
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DOI: 10.1002/adma.202101190
Abstract: The growing enthusiasm for cancer immunotherapies and adoptive cell therapies has prompted increasing interest in biomaterials development mimicking natural antigen-presenting cells (APCs) for T-cell expansion. In contrast to conventional bottom-up approaches aimed at layering synthetic… read more here.
Keywords: intracellular hydrogelation; dendritic cells; antigen; antigen presenting ... See more keywords
Engineering Cyborg Bacteria Through Intracellular Hydrogelation
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DOI: 10.1002/advs.202204175
Abstract: Natural and artificial cells are two common chassis in synthetic biology. Natural cells can perform complex tasks through synthetic genetic constructs, but their autonomous replication often causes safety concerns for biomedical applications. In contrast, artificial… read more here.
Keywords: intracellular hydrogelation; cyborg; engineering cyborg; cyborg bacteria ... See more keywords