Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2021.113948
Abstract: Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics, one of which involves pathogens invading and forming reservoirs within host cells. Due to the poor cell membrane permeability, stability… read more here.
Keywords: intracellular infections; drug delivery; conventional antibiotics; repurposing conventional ... See more keywords
Biological macromolecules based targeted nanodrug delivery systems for the treatment of intracellular infections.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.030
Abstract: Intracellular infections are tricky to treat, the reason being the poor penetration of antibiotics/antimycotics into the microbial niche (host cell). Macrophages are primary targets of facultative and obligate intracellular bacteria/fungi to be abused as host… read more here.
Keywords: intracellular infections; macromolecules based; biological macromolecules; targeted nanodrug ... See more keywords