Streptozotocin-Induced Autophagy Reduces Intracellular Insulin in Insulinoma INS-1E Cells.
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DOI: 10.1089/dna.2017.3874
Abstract: Streptozotocin (STZ), a glucose analog, induces diabetes in experimental animals by inducing preferential cytotoxicity in pancreatic beta cells. We investigated whether STZ reduced the production of intracellular insulin through autophagy in insulinoma INS-1E cells. Typically,… read more here.
Keywords: insulin; insulinoma ins; stz; streptozotocin ... See more keywords