Biomineralization of magnetic nanoparticles in stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d3nr00863k
Abstract: Iron is one of the most common metals in the human body, with an intrinsic metabolism including proteins involved in its transport, storage, and redox mechanisms. A less explored singularity is the presence of magnetic… read more here.
Keywords: iron; biomineralization magnetic; magnetic nanoparticles; intracellular iron ... See more keywords
Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.159235
Abstract: Systemic iron metabolism is disrupted in chronic kidney disease (CKD). However, little is known about local kidney iron homeostasis and its role in kidney fibrosis. Kidney-specific effects of iron therapy in CKD also remain elusive.… read more here.
Keywords: kidney; iron; therapy; intracellular iron ... See more keywords
Role of the hepcidin-ferroportin axis in pathogen-mediated intracellular iron sequestration in human phagocytic cells.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2017015255
Abstract: Upon infection, pathogen and host compete for the same iron pool, because this trace metal is a crucial micronutrient for all living cells. Iron dysregulation in the host is strongly associated with poor outcomes in… read more here.
Keywords: iron; hepcidin ferroportin; iron sequestration; intracellular iron ... See more keywords
Helicobacter pylori infection perturbs iron homeostasis in gastric epithelial cells
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DOI: 10.1371/journal.pone.0184026
Abstract: The iron deficiency anaemia that often accompanies infection with Helicobacter pylori may reflect increased uptake of iron into gastric epithelial cells. Here we show an infection-associated increase in total intracellular iron levels was associated with… read more here.
Keywords: gastric epithelial; epithelial cells; intracellular iron; infection ... See more keywords
Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032420
Abstract: Cytochrome P450 (CYP) 1B1 is a heme-containing monooxygenase found mainly in extrahepatic tissues, including the retina. CYP1B1 substrates include exogenous aromatic hydrocarbons, such as dioxins, and endogenous bioactive compounds, including 17β-estradiol (E2) and arachidonic acid.… read more here.
Keywords: iron; oxidative stress; cyp1b1; expression ... See more keywords