Thermal stress and selection for growth affect myogenic satellite cell lipid accumulation and adipogenic gene expression through mechanistic target of rapamycin pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of animal science"
DOI: 10.1093/jas/skac001
Abstract: Satellite cells (SCs) are multipotential stem cells having the plasticity to convert to an adipogenic lineage in response to thermal stress during the period of peak mitotic activity (the first week after hatch in poultry).… read more here.
Keywords: intracellular lipid; thermal stress; accumulation; lipid accumulation ... See more keywords
Specific knock‐down of tissue non‐specific alkaline phosphatase mRNA levels inhibits intracellular lipid accumulation in 3T3‐L1 and HepG2 cells
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Experimental Pathology"
DOI: 10.1111/iep.12243
Abstract: The use of non‐specific inhibitors of tissue non‐specific alkaline phosphatase (TNSALP) in pre‐adipocytes blocks intracellular lipid accumulation. TNSALP is also expressed in hepatocytes, which are known to accumulate lipid in a similar manner to pre‐adipocytes.… read more here.
Keywords: intracellular lipid; non specific; lipid accumulation; hepg2 cells ... See more keywords
The Modulation of Blue-Light-Induced Inflammation, Intracellular Lipid Secretion, and Oxidative Stress in Sebocytes with Cannabidiol.
Sign Up to like & getrecommendations! Published in 2022 at "Photochemistry and photobiology"
DOI: 10.1111/php.13764
Abstract: Light-induced skin damage leads to cellular or molecular dysfunction, thus potentially causing different skin issues (e.g., skin aging, seborrheic dermatitis and pigmentation). Blue light, a potent visible light that was previously adopted for promoting skin… read more here.
Keywords: light induced; intracellular lipid; blue light; light ... See more keywords
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aaz4564
Abstract: APOE4-disrupted intracellular lipid homeostasis in human and yeast cells was reversed by promoting phospholipid synthesis through choline supplementation. APOE4 disrupts lipid homeostasis in glia APOE4 is a strong genetic risk factor for many diseases, most… read more here.
Keywords: intracellular lipid; ipsc derived; apoe4; lipid homeostasis ... See more keywords
FT-NIR: a tool for rapid intracellular lipid quantification in oleaginous yeasts
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology for Biofuels"
DOI: 10.1186/s13068-019-1513-9
Abstract: BackgroundLipid extraction for quantification of fat content in oleaginous yeasts often requires strong acids and harmful organic solvents; it is laborious and time-consuming. Therefore, in most cases just endpoint measurements of lipid accumulation are performed… read more here.
Keywords: extraction; intracellular lipid; content; oleaginous yeasts ... See more keywords
Intracellular Lipid Accumulation Drives the Differentiation of Decidual Polymorphonuclear Myeloid-Derived Suppressor Cells via Arachidonic Acid Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.868669
Abstract: Decidual polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are essential to immune tolerance during pregnancy. A reduction in the number of these cells is associated with unexplained recurrent pregnancy loss (URPL). In our previous study, we reported… read more here.
Keywords: pmn mdscs; intracellular lipid; arachidonic acid; lipid accumulation ... See more keywords
GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.00576
Abstract: Gene-associated with retinoid-interferon-induced mortality 19 (GRIM-19) targets multiple signaling pathways involved in cell death and growth. However, the role of GRIM-19 in the pathogenesis of hepatitis virus infections remains unexplored. Here, we investigated the restrictive… read more here.
Keywords: intracellular lipid; lipid accumulation; hcv replication; attenuating intracellular ... See more keywords
Fasudil Increased the Sensitivity to Gefitinib in NSCLC by Decreasing Intracellular Lipid Accumulation
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DOI: 10.3390/cancers14194709
Abstract: Simple Summary The anti-tumor role of Fasudil in EGFR-mutation NSCLC as well as its mechanism are largely unknown. Here, we show that Fasudil could effectively inhibit EGFR-mutation cell growth and enhance the sensitivity of gefitinib-resistant… read more here.
Keywords: fasudil; gefitinib; intracellular lipid; lipid accumulation ... See more keywords