Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24127-3
Abstract: To be effective, chemotherapy against tuberculosis (TB) must kill the intracellular population of the pathogen, Mycobacterium tuberculosis. However, how host cell microenvironments affect antibiotic accumulation and efficacy remains unclear. Here, we use correlative light, electron,… read more here.
Keywords: accumulation; intracellular localisation; efficacy; tuberculosis ... See more keywords
Virulence Mechanisms of Common Uropathogens and Their Intracellular Localisation within Urothelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11080926
Abstract: A recurrent urinary tract infection (UTI) is a common debilitating condition whereby uropathogens are able to survive within the urinary tract. In this study, we aimed to determine if the common uropathogens Escherichia coli, Enterococcus… read more here.
Keywords: intracellular localisation; urothelial cells; common uropathogens; virulence mechanisms ... See more keywords