Dynamic intracellular mechanical cues facilitate collective signaling responses
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DOI: 10.1016/j.isci.2021.102396
Abstract: Summary Collective behavior emerges in diverse life machineries, e.g., the immune responses to dynamic stimulations. The essential questions that arise here are that whether and how cells in vivo collectively respond to stimulation frequencies higher… read more here.
Keywords: dynamic intracellular; mechanical cues; intracellular mechanical; signaling responses ... See more keywords
Lipid droplets are intracellular mechanical stressors that impair hepatocyte function
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DOI: 10.1073/pnas.2216811120
Abstract: Significance Deformation of the nucleus as a result of extracellular sources of stress, including increased substrate stiffness, constricted migration, and compression, has been well documented to lead to increased nuclear rupture, changes in gene expression,… read more here.
Keywords: lipid droplets; hepatocyte function; droplets intracellular; intracellular mechanical ... See more keywords