LAUSR

Intracellular Receptor Modulation: Novel Approach to Target GPCRs.

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0 Published in 2018 at "Trends in pharmacological sciences"

DOI: 10.1016/j.tips.2018.03.002

Abstract: Recent crystal structures of multiple G protein-coupled receptors (GPCRs) have revealed a highly conserved intracellular pocket that can be used to modulate these receptors from the inside. This novel intracellular site partially overlaps with the… read more here.

Keywords: intracellular receptor; approach target; novel approach; modulation novel ... See more keywords