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   Articles with "intracellular replication" as a keyword



Identification of a Coxiella burnetii outer membrane porin required for intracellular replication

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recommendations! Published in 2025 at "Infection and Immunity"

DOI: 10.1128/iai.00448-24

Abstract: ABSTRACT Coxiella burnetii is a gram-negative, obligate intracellular pathogen that causes human Q fever. Within host cells, C. burnetii proliferates in a spacious, acidic, lysosome-derived Coxiella-containing vacuole (CCV) by a process that requires the Dot/Icm… read more here.

Keywords: replication; coxiella burnetii; cbu0937; intracellular replication ... See more keywords

TRIM56-mediated production of type I interferon inhibits intracellular replication of Rickettsia rickettsii

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recommendations! Published in 2024 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03695-23

Abstract: ABSTRACT Rickettsia rickettsii (R. rickettsii), the causative agent of Rocky Mountain spotted fever (RMSF), is the most pathogenic member among Rickettsia spp. Previous studies have shown that tripartite motif-containing 56 (TRIM56) E3 ligase-induced ubiquitination of… read more here.

Keywords: host; trim56; interferon; intracellular replication ... See more keywords

Identification of the Francisella novicida FTN_0096 as a factor involved in intracellular replication and host response

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recommendations! Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0329626

Abstract: Francisella tularensis is the causative agent of the zoonotic disease tularemia. We investigated a pathogenic factor of F. tularensis subsp. novicida (F. novicida). Accordingly, we established a novel infection model using HeLa cells. F. novicida… read more here.

Keywords: ftn; novicida; factor; intracellular replication ... See more keywords

Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts

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recommendations! Published in 2025 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1013525

Abstract: Therapeutic failures and relapses are critical challenges in Staphylococcus aureus bone and joint infections. These issues may stem, in part, from the incomplete eradication of S. aureus residing within osteoblasts, the bone-forming cells, despite recommended… read more here.

Keywords: aureus; replication dynamics; high proportion; intracellular replication ... See more keywords

The Coxiella burnetii T4SS Effector AnkF Is Important for Intracellular Replication

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recommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2020.559915

Abstract: Coxiella burnetii is an obligate intracellular pathogen and the causative agent of the zoonotic disease Q fever. Following uptake by alveolar macrophages, the pathogen replicates in an acidic phagolysosomal vacuole, the C. burnetii-containing vacuole (CCV).… read more here.

Keywords: ankf; ccv; coxiella burnetii; intracellular replication ... See more keywords