PSMA-Targeted Intracellular Self-Assembled Probe for Enhanced PET Imaging.
Sign Up to like & getrecommendations! Published in 2024 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00572
Abstract: Positron-emission tomography (PET) offers high sensitivity for cancer diagnosis. However, small-molecule-based probes often exhibit insufficient accumulation in tumor sites, while nanoparticle-based agents typically have limited delivery efficiency. To address this challenge, this study proposes a… read more here.
Keywords: pet imaging; cancer; intracellular self; psma ... See more keywords
An in Situ Intracellular Self-Assembly Strategy for Quantitatively and Temporally Monitoring Autophagy.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.6b07843
Abstract: Autophagy plays a crucial role in the metabolic process. So far, conventional methods are incapable of rapid, precise, and real-time monitoring of autophagy in living objects. Herein, we describe an in situ intracellular self-assembly strategy… read more here.
Keywords: self assembly; assembly strategy; situ intracellular; monitoring autophagy ... See more keywords
Effects of Hydrophobic Residues on the Intracellular Self-Assembly of De Novo Designed Peptide Tags and Their Orthogonality.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00058
Abstract: Protein assemblies forming nano- to micro-sized structures underlie versatile biological events in living systems. For mimicking and engineering these protein assemblies through a bottom-up approach, self-assembling peptides (SAPs) that form nanofibril structures via β-sheets serve… read more here.
Keywords: self assembly; hydrophobic residues; peptide; intracellular self ... See more keywords
Intracellular self-assembly and metabolite analysis of key enzymes for L-lysine synthesis based on key components of cellulosomes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1596240
Abstract: Introduction Cellulosome is a natural multi-enzyme complex in the extracellular space of anaerobic microorganisms, which has the advantages of small molecular weight, multiple binding sites, and strong designability. This study aimed to explore the influence… read more here.
Keywords: engineered bacteria; multi enzyme; intracellular self; enzyme ... See more keywords