Articles with "intracellular signalling" as a keyword



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RAS nanoclusters are cell surface transducers that convert extracellular stimuli to intracellular signalling

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Published in 2023 at "FEBS Letters"

DOI: 10.1002/1873-3468.14569

Abstract: Mutations of rat sarcoma virus (RAS) oncogenes (HRAS, KRAS and NRAS) can contribute to the development of cancers and genetic disorders (RASopathies). The spatiotemporal organization of RAS is an important property that warrants further investigation.… read more here.

Keywords: stimuli intracellular; transducers convert; cell surface; extracellular stimuli ... See more keywords
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Phosphorylation of intracellular signalling molecules in peripheral blood cells from patients with psoriasis on originator or biosimilar infliximab

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Published in 2018 at "British Journal of Dermatology"

DOI: 10.1111/bjd.16269

Abstract: Psoriasis vulgaris is a chronic, inflammatory skin disease characterized by a dysregulated immune response and it is associated with substantial systemic comorbidities. Biological drugs such as tumour necrosis factor (TNF)‐α inhibitors can ameliorate the disease… read more here.

Keywords: phosphorylation intracellular; originator; signalling molecules; molecules peripheral ... See more keywords
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Cancer-Related Intracellular Signalling Pathways Activated by DOXorubicin/Cyclodextrin-Graphene-Based Nanomaterials

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12010063

Abstract: In the last decade, nanotechnological progress has generated new opportunities to improve the safety and efficacy of conventional anticancer therapies. Compared with other carriers, graphene nanoplatforms possess numerous tunable functionalities for the loading of multiple… read more here.

Keywords: cancer; related intracellular; cancer related; signalling pathways ... See more keywords