Intracerebral microdialysis coupled to LC-MS/MS for the determination tramadol and its major pharmacologically active metabolite O-desmethyltramadol in rat brain microdialysates.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2157
Abstract: A rapid and sensitive method involving liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) coupled to an intracerebral microdialysis technique was developed for the determination and pharmacokinetic investigation of tramadol and its major active metabolite O-desmethyltramadol… read more here.
Keywords: rat brain; microdialysis; intracerebral microdialysis; tramadol ... See more keywords
P19 Intracerebral microdialysis studies on the role of Pinocembrin on CYP3A in rat
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.06.020
Abstract: Propolis is one of the most heterogeneous natural product of plant origin. Research on the flavonoids in propolis has been prompted by their beneficial effects on health. In propolis, pinocembrin (5,7-dihydroxyflavanone) is the flavonoid that… read more here.
Keywords: cyp3a rat; pinocembrin cyp3a; intracerebral microdialysis; rat brain ... See more keywords