Hyaluronan‐based dissolving microneedles with high antigen content for intradermal vaccination: Formulation, physicochemical characterization and immunogenicity assessment
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.11.013
Abstract: Graphical abstract Figure. No caption available. Abstract The purpose of this study was to optimize the manufacturing of dissolving microneedles (dMNs) and to increase the antigen loading in dMNs to investigate the effect on their… read more here.
Keywords: dissolving microneedles; high antigen; antigen; intradermal vaccination ... See more keywords
Enhanced immunity in intradermal vaccination by novel hollow microneedles
Sign Up to like & getrecommendations! Published in 2018 at "Skin Research and Technology"
DOI: 10.1111/srt.12576
Abstract: The intradermal (ID) route for vaccination represents an effective alternative to subcutaneous (SC)/intramuscular administration to induce protective immunity. However, a critical issue associated with ID vaccination is the precise delivery of solution in the upper… read more here.
Keywords: immunity; immunity intradermal; vaccination novel; intradermal vaccination ... See more keywords
Safety and immunogenicity of intradermal administration of fractional dose CoronaVac®, ChAdOx1 nCoV-19 and BNT162b2 as primary series vaccination
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DOI: 10.3389/fimmu.2022.1010835
Abstract: There is a limited supply of COVID-19 vaccines, with less than 20% of eligible populations in low-income countries having received one dose. Intradermal delivery of fractional dose vaccines is one way to improve global vaccine… read more here.
Keywords: vaccination; series; intradermal vaccination; bnt162b2 ... See more keywords
Self-Assembly DNA Polyplex Vaccine inside Dissolving Microneedles for High-Potency Intradermal Vaccination
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DOI: 10.7150/thno.19894
Abstract: The strong immunogenicity induction is the powerful weapon to prevent the virus infections. This study demonstrated that one-step synthesis of DNA polyplex vaccine in microneedle (MN) patches can induce high immunogenicity through intradermal vaccination and… read more here.
Keywords: polyplex vaccine; dna polyplex; intradermal vaccination; vaccine ... See more keywords