Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29585
Abstract: β‐Catenin, the downstream effector of the Wnt signaling, plays important roles in hepatic development, regeneration, and tumorigenesis. However, its role at hepatocyte adherens junctions (AJ) is relatively poorly understood, chiefly due to spontaneous compensation by… read more here.
Keywords: dual catenin; catenin; intrahepatic cholestasis; cholestasis ... See more keywords
Plectin Mutations in Progressive Familial Intrahepatic Cholestasis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30841
Abstract: Neonates and infants are susceptible to cholestatic liver diseases. At least six genes are causative for progressive familial intrahepatic cholestasis (PFIC), and more genetic defects are known to cause infant cholestasis.(1) Approximately one-third of PFIC… read more here.
Keywords: familial intrahepatic; plec; progressive familial; intrahepatic cholestasis ... See more keywords
Combining newborn metabolic and genetic screening for neonatal intrahepatic cholestasis caused by citrin deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12206
Abstract: To evaluate the feasibility of incorporating genetic screening for neonatal intrahepatic cholestasis, caused by citrin deficiency (NICCD), into the current newborn screening (NBS) program. We designed a high‐throughput iPLEX genotyping assay to detect 28 SLC25A13… read more here.
Keywords: genetic screening; screening; cholestasis caused; screening neonatal ... See more keywords
Contraceptive vaginal ring-induced cholestasis in a patient with a history of intrahepatic cholestasis of pregnancy.
Sign Up to like & getrecommendations! Published in 2020 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.06.002
Abstract: INTRODUCTION Intrahepatic cholestasis of pregnancy (ICP) is a heterogeneous group of liver disorders with a high recurrence rate. Patients with a history of ICP are at risk of developing contraceptive-induced cholestasis, especially if they harbour… read more here.
Keywords: cholestasis pregnancy; intrahepatic cholestasis; history; induced cholestasis ... See more keywords
Intrahepatic cholestasis of pregnancy in conjunction with a frameshift deletion in FGFR4.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2021.101800
Abstract: Intrahepatic cholestasis of pregnancy (ICP) is characterized by increased serum bile acid levels in the third trimester of pregnancy, and resolves quickly after delivery. We present the case of a 29-year-old woman who developed idiopathic… read more here.
Keywords: pregnancy; pregnancy conjunction; cholestasis pregnancy; deletion ... See more keywords
Elevated international normalized ratio (INR) and new diagnosis of hepatitis C associated with severe intrahepatic cholestasis of pregnancy (ICP): A case report
Sign Up to like & getrecommendations! Published in 2020 at "Case Reports in Women's Health"
DOI: 10.1016/j.crwh.2020.e00178
Abstract: Background Severe intrahepatic cholestasis of pregnancy (ICP), defined as a serum bile acid (SBA) level > 100 μmol/l, remains poorly understood in its mechanism and implications. Case A patient with a missed diagnosis of mild… read more here.
Keywords: pregnancy icp; hepatitis; severe intrahepatic; cholestasis pregnancy ... See more keywords
Coenzyme Q 10 supplementation: A potential therapeutic option for the treatment of intrahepatic cholestasis of pregnancy.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173270
Abstract: Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy specific liver disease characterized by pruritus, elevated serum bile acids and abnormal liver function that may be associated with severe adverse pregnancy outcomes. We previously reported that… read more here.
Keywords: supplementation; pregnancy; cholestasis pregnancy; coq10 ... See more keywords
TianJiu therapy for α-naphthyl isothiocyanate-induced intrahepatic cholestasis in rats treated with fresh Ranunculus sceleratus L.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112310
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE TianJiu (TJ) therapy, one type of cold moxibustion, applies to specific acupuncture points with herbal patches of hot nature, providing a constant irritant to the skin until the presence of hyperemia and blistering.… read more here.
Keywords: treatment; treatment fresh; intrahepatic cholestasis; therapy ... See more keywords
419. Detection of additional abnormalities or co-morbidities in women with intrahepatic cholestasis of pregnancy
Sign Up to like & getrecommendations! Published in 2018 at "Pregnancy Hypertension"
DOI: 10.1016/j.preghy.2018.08.146
Abstract: Introduction Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-specific liver disease, affecting around0.7% of pregnancies. It is a multifactorial condition with genetic, hormonal and environmental components. ICP is a diagnosis of exclusion, and… read more here.
Keywords: detection; pregnancy; cholestasis pregnancy; raised bile ... See more keywords
Prevalence and risk factors of intrahepatic cholestasis of pregnancy in a Chinese population
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73378-5
Abstract: Studies on the risk factors for intrahepatic cholestasis of pregnancy (ICP) in a population-based cohort are lacking. We assess the prevalence and risk factors of ICP in a Chinese population. In this study, a cohort… read more here.
Keywords: factors intrahepatic; pregnancy; risk factors; intrahepatic cholestasis ... See more keywords
Vaginal Progesterone Is Associated with Intrahepatic Cholestasis of Pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Perinatology"
DOI: 10.1055/a-2081-2573
Abstract: Abstract Objective The frequency of intrahepatic cholestasis of pregnancy (ICP) peaks during the third trimester of pregnancy when plasma progesterone levels are the highest. Furthermore, twin pregnancies are characterized by higher progesterone levels than singletons… read more here.
Keywords: cholestasis; cholestasis pregnancy; vaginal progesterone; progesterone ... See more keywords