Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load
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DOI: 10.1371/journal.pcbi.1010756
Abstract: Background Infection with human immunodeficiency virus type 1 (HIV) typically results from transmission of a small and genetically uniform viral population. Following transmission, the virus population becomes more diverse because of recombination and acquired mutations… read more here.
Keywords: hiv; genetic diversity; diversity; intrahost genetic ... See more keywords
Intrahost Genetic Diversity of Dengue Virus in Human Hosts and Mosquito Vectors under Natural Conditions Which Impact Replicative Fitness In Vitro
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DOI: 10.3390/v15040982
Abstract: Dengue virus (DENV) is an arbovirus whose transmission cycle involves disparate hosts: humans and mosquitoes. The error-prone nature of viral RNA replication drives the high mutation rates, and the consequently high genetic diversity affects viral… read more here.
Keywords: genetic diversity; diversity; intrahost genetic; mosquito ... See more keywords