In vitro characterization of the intramelanosomal domain of human recombinant TYRP1 and its oculocutaneous albinism type 3‐related mutant variants
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DOI: 10.1002/pro.4518
Abstract: Tyrosinase related protein 1 (TYRP1) is the most abundant melanosomal protein of the melanocyte, where plays an important role in the synthesis of eumelanin, possibly catalyzing the oxidation of 5,6‐dihydroxyindole‐2‐carboxylic acid to 5,6‐quinone‐2‐carboxylic acid. Mutations… read more here.
Keywords: tyrp1; domain; intramelanosomal domain; oculocutaneous albinism ... See more keywords