Palladium-catalyzed intramolecular C H acylation of indoles with thioester
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DOI: 10.1016/j.tetlet.2019.151061
Abstract: Abstract A palladium-catalyzed intramolecular C H acylation of indole with thioester is described, providing a direct and effective approach for the synthesis of the biologically active indole-indolone scaffolds. The method obviates the need for the… read more here.
Keywords: intramolecular acylation; acylation indoles; indoles thioester; palladium catalyzed ... See more keywords
Rhodium-Catalyzed Intramolecular Acylation of 2-(Indol-1-yl)benzoic Acids under Redox-Neutral Conditions
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DOI: 10.1055/a-2088-9106
Abstract: We developed a novel access to indoloindolone by a rhodium-catalyzed intramolecular acylation of 2-(indol-1-yl)benzoic acids. This reaction proceeds via the in situ formation of a mixed anhydride under redox-neutral reaction conditions. Preliminary mechanistic investigations revealed… read more here.
Keywords: catalyzed intramolecular; indol benzoic; intramolecular acylation; rhodium catalyzed ... See more keywords
Direct Deoxygenative Intramolecular Acylation of Biarylcarboxylic Acids
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DOI: 10.1055/s-0040-1707246
Abstract: A photocatalyzed intramolecular cyclization is developed for the synthesis of fluorenones. In this photoredox reaction, triphenylphosphine is used as an inexpensive and effective deoxygenative reagent for biarylcarboxylic acids to give acyl radicals, which quickly undergo… read more here.
Keywords: acylation biarylcarboxylic; biarylcarboxylic acids; intramolecular acylation; direct deoxygenative ... See more keywords