Rhodium(III)-Catalyzed Intramolecular Annulation and Aromatization for the Synthesis of Pyrrolo[1,2-a]quinolines.
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DOI: 10.1021/acs.orglett.3c00321
Abstract: A rhodium(III)-catalyzed protocol for the synthesis of pyrrolo[1,2-a]quinolines through intramolecular annulation of o-alkynyl amino aromatic ketones and subsequent aromatization is reported. This transformation builds the pyrrole and quinoline moieties of the pyrrolo[1,2-a]quinoline in one pot… read more here.
Keywords: intramolecular annulation; pyrrolo quinolines; rhodium iii; synthesis pyrrolo ... See more keywords
NBS-induced intramolecular annulation reactions for the divergent synthesis of fused- and spirocyclic indolines.
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DOI: 10.1039/d3cc01920a
Abstract: An NBS-induced intramolecular annulation of 3-(1H-indol-3-yl)-N-alkoxypropanamide is described. The reactions proceed well and quickly under mild conditions with the help of a base. It was found that C2-substituents on the indole ring in 3-(1H-indol-3-yl)-N-alkoxypropanamide have… read more here.
Keywords: nbs induced; intramolecular annulation; induced intramolecular; divergent synthesis ... See more keywords
Organocatalytic intramolecular (4 + 2) annulation of enals with ynamides: atroposelective synthesis of axially chiral 7-aryl indolines
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DOI: 10.1039/d3sc01880f
Abstract: Catalytic enantioselective transformation of alkynes has become a powerful tool for the synthesis of axially chiral molecules. Most of these atroposelective reactions of alkynes rely on transition-metal catalysis, and the organocatalytic approaches are largely limited… read more here.
Keywords: enals ynamides; annulation enals; chiral aryl; intramolecular annulation ... See more keywords