Intramolecular Appel Reaction of Trifluoromethylated β-Keto Diazos Enabling Assembly of Trifluoromethylpyrazoles.
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DOI: 10.1021/acs.orglett.2c00738
Abstract: A method for the generation of trifluoromethylated β-keto diazos and their applications in intramolecular Appel type reactions are reported. The key success of this reaction is a diazo species as an N-nucleophile in Appel reactions.… read more here.
Keywords: trifluoromethylated keto; reaction; keto diazos; intramolecular appel ... See more keywords