Intramolecular Azide–Alkene Cycloaddition—The Logothetis Reaction
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DOI: 10.1002/ejoc.202500472
Abstract: The assembly of cyclic amines is fundamental to medicinal chemistry. While intramolecular azide–alkyne cycloaddition is widely practiced, intramolecular azide–alkene cycloaddition is much less used, even though it has been known since 1965. This review is… read more here.
Keywords: chemistry; alkene cycloaddition; intramolecular azide; azide alkene ... See more keywords
A new route to 1,2,3-triazole fused benzooxazepine and benzodiazepine analogues through metal-free intramolecular azide-olefin oxidative cycloaddition
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151164
Abstract: Abstract A collection of 1,2,3-triazole fused benzooxazepine and benzodiazepine analogues was prepared by one pot azide substitution and intramolecular azide-olefin oxidative cycloaddition sequence under metal-free conditions. read more here.
Keywords: benzooxazepine benzodiazepine; intramolecular azide; azide olefin; triazole fused ... See more keywords