p67phox binds to a newly identified site in Nox2 following the disengagement of an intramolecular bond—Canaan sighted?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a1219-607r
Abstract: Activation of the phagocyte NADPH oxidase involves a conformational change in Nox2. The effector in this process is p67phox and there is evidence for a change in the configuration of p67phox being required for binding… read more here.
Keywords: intramolecular bond; nox2; site; p67phox ... See more keywords
Formation of silaimines from a sterically demanding iminophosphonamido chlorosilylene via intramolecular N-P bond cleavage.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc02812j
Abstract: The sterically demanding iminophosphonamido chlorosilylene [Ph2P(DipN)2]SiCl (Dip = 2,6-diisopropylphenyl) was synthesized and fully characterized using NMR spectroscopy and X-ray crystallography. Substitution reactions of [Ph2P(DipN)2]SiCl with N- and Fe-nucleophiles led to the unexpected formation of the… read more here.
Keywords: intramolecular bond; sterically demanding; via intramolecular; demanding iminophosphonamido ... See more keywords
H-bond cooperativity: polarisation effects on secondary amides
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DOI: 10.1039/d2sc04271a
Abstract: Formation of a H-bond with an amide carbonyl oxygen atom increases the strength of subsequent H-bonds formed by the amide NH, due to polarisation of the bond. The magnitude of this effect has been quantified… read more here.
Keywords: polarisation; cooperativity; group; intramolecular bond ... See more keywords
Intramolecular C-N Bond Formation via Thermal Arene C-H Bond Activation Supported by Au(III) Complexes
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DOI: 10.3390/ma14071676
Abstract: One of the main tactics to access C-N bonds from inactivated C-H functionalities is direct transition metal-supported aminations. Due to the often harsh reaction conditions, the current goal in the field is the search for… read more here.
Keywords: intramolecular bond; formation via; via thermal; bond formation ... See more keywords
Synthesis of 2-Cyanobenzothiazoles via Pd-Catalyzed/Cu-Assisted C-H Functionalization/Intramolecular C-S Bond Formation from N-Arylcyanothioformamides
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238426
Abstract: We report herein on a catalytic system involving palladium and copper to achieve the cyclization of N-arylcyanothioformamides and the synthesis of 2-cyanobenzothiazoles. The C-H functionalization/intramolecular C-S bond formation reaction was achieved in the presence of… read more here.
Keywords: functionalization intramolecular; synthesis cyanobenzothiazoles; bond formation; intramolecular bond ... See more keywords