Centipede venom peptide SsmTX‐I with two intramolecular disulfide bonds shows analgesic activities in animal models
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.2988
Abstract: Pain is a major symptom of many diseases and results in enormous pressures on human body or society. Currently, clinically used analgesic drugs, including opioids and nonsteroidal anti‐inflammatory drugs, have adverse reactions, and thus, the… read more here.
Keywords: peptide; intramolecular disulfide; centipede venom; analgesic activities ... See more keywords
The essential cysteines in the CIPC motif of the thioredoxin-like Trypanosoma brucei MICOS subunit TbMic20 do not form an intramolecular disulfide bridge in vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2022.111463
Abstract: The mitochondrial protein import machinery of trypanosomatids is highly divergent from that of the well-studied models such as baker's yeast. A notable example is that the central catalyst of the mitochondrial intermembrane space import and… read more here.
Keywords: disulfide; form; micos; intramolecular disulfide ... See more keywords
Online Electrochemical Reduction of Both Inter- and Intramolecular Disulfide Bridges in Immunoglobulins.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04261
Abstract: Electrochemical reduction of intermolecular disulfide bridges has previously been demonstrated in immunoglobulins but failed to achieve reduction of intramolecular bonds. We now report an improved method that achieves the full reduction of both intermolecular and… read more here.
Keywords: electrochemical reduction; intramolecular disulfide; online electrochemical; reduction ... See more keywords
Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.05085-22
Abstract: Streptococcus gallolyticus subsp. gallolyticus (SGG), previously named Streptococcus bovis biotype I, is an opportunistic pathogen responsible for invasive infections (septicemia, endocarditis) in elderly people and is often associated with colon tumors. SGG is one of… read more here.
Keywords: gallocin; glla1 glla2; intramolecular disulfide; peptide ... See more keywords
Effect of intramolecular disulfide bond of bovine lactoferricin on its molecular structure and antibacterial activity against Trueperella pyogenes separated from cow milk with mastitis
Sign Up to like & getrecommendations! Published in 2020 at "BMC Veterinary Research"
DOI: 10.1186/s12917-020-02620-z
Abstract: Background Lactoferricin (Lfcin) is an antimicrobial activity center of lactoferrin, produced by hydrolysis from the N-terminal of lactoferrin. It was hypothesized that the intramolecular disulfide bond in Lfcin could affect its antibacterial function through influencing… read more here.
Keywords: disulfide bond; intramolecular disulfide; blfcin; structure ... See more keywords