Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b01089
Abstract: Hydroalkoxylation is a powerful and efficient method of forming C-O bonds and cyclic ethers in synthetic chemistry. In studying the biosynthesis of the fungal natural product herqueinone, we identified an enzyme that can perform an… read more here.
Keywords: hydroalkoxylation; enantioselective hydroalkoxylation; reaction; enzyme catalyzed ... See more keywords
Palladium-catalyzed intramolecular enantioselective C(sp3)–H insertion of donor/donor carbenes
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc03524c
Abstract: Herein, the first palladium-catalyzed intramolecular enantioselective C(sp3)–H insertion reaction of donor–donor carbenes has been successfully achieved. This facile protocol enables the rapid construction of a collection of enantioenriched decorated indolines with two contiguous stereocenters in… read more here.
Keywords: donor donor; catalyzed intramolecular; palladium catalyzed; intramolecular enantioselective ... See more keywords