Pd-Catalyzed Cascade Intramolecular Heck Cyclization/Dearomatization of Indoles for the Construction of Two All-Carbon Quaternary Centers.
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DOI: 10.1021/acs.orglett.2c03691
Abstract: A facile Pd-catalyzed cascade of intramolecular Heck cyclization/alkylpalladium activated dearomatization of aryl alkyne-tethered indole is described. In this single step two nonadjacent all-carbon quaternary centers, two nitrogen-containing heterocycles, and three C(sp2)-C(sp3) bonds are efficiently furnished.… read more here.
Keywords: intramolecular heck; catalyzed cascade; cascade intramolecular; carbon quaternary ... See more keywords