PhI-Catalyzed Intramolecular Oxidative Coupling Toward Synthesis of 2-Amino-1,3,4-Thiadizoles
Sign Up to like & getrecommendations! Published in 2018 at "Catalysis Letters"
DOI: 10.1007/s10562-018-2541-y
Abstract: AbstractA highly efficient method for the synthesis of thiadiazole derivatives via intramolecular oxidative coupling of thiosemicarbazide, using the in situ generated hypervalent iodine(III) reagents is developed. The protocol can be carried out smoothly and provides… read more here.
Keywords: phi catalyzed; intramolecular oxidative; oxidative coupling; thiadiazole derivatives ... See more keywords
Enantioselective Intramolecular Oxidative Aminoacetoxylation from Aryl-Substituted Alkene via Chiral Triazole-oxazoline Palladium Complexes.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c03248
Abstract: Here, we describe an enantioselective intramolecular oxidative aminoacetoxylation reaction using a palladium catalyst and an aryl-substituted internal alkene compound as the substrate under mild conditions in several hours. The triazole-oxazoline ligand was selected for the… read more here.
Keywords: triazole oxazoline; intramolecular oxidative; aryl substituted; enantioselective intramolecular ... See more keywords
Construction of Bisbenzofuro[2,3-b:3',2'-e]pyridines by Palladium-Catalyzed Double Intramolecular Oxidative C-H/C-H Coupling.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b00323
Abstract: The palladium-catalyzed intramolecular oxidative C-H/C-H coupling of 2-aryloxypyridines as challenging substrates is investigated to construct an important class of N,O-mixed heteroacenes, i.e. benzofuropyridines. It is found that 2,6-diaryloxypyridines efficiently undergo double cyclization to provide bisbenzofuro[2,3-b:3',2'-e]pyridines… read more here.
Keywords: bisbenzofuro pyridines; palladium catalyzed; intramolecular oxidative; oxidative coupling ... See more keywords
Concise Enantioselective Total Synthesis of Daphenylline Enabled by an Intramolecular Oxidative Dearomatization.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01674
Abstract: Daphenylline is a structurally unique member of the triterpenoid Daphniphyllum natural alkaloids, which exhibit intriguing biological activities. Six total syntheses have been reported, five of which utilize aromatization approaches. Herein, we report a concise protecting-group-free… read more here.
Keywords: concise; intramolecular oxidative; oxidative dearomatization; total synthesis ... See more keywords
Metal- and Reagent-Free Intramolecular Oxidative Amination of Tri- and Tetrasubstituted Alkenes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b01016
Abstract: A metal- and reagent-free, electrochemical intramolecular oxidative amination reaction of tri- and tetrasubstituted alkenes has been developed. The electrosynthetic method proceeds through radical cyclization to form the key C-N bond, allowing a variety of hindered… read more here.
Keywords: oxidative amination; intramolecular oxidative; amination; tri tetrasubstituted ... See more keywords
I2-catalyzed intramolecular oxidative amination of C(sp3)–H bond: efficient access to 3-acylimidazo[1,2-a]pyridines under neat condition
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra10118c
Abstract: An efficient and “green” protocol for the synthesis of 3-acylimidazo[1,2-a]pyridines through intramolecular oxidative α-amination of carbonyl compounds has been developed. The reaction proceeds smoothly utilizing I2 as a catalyst and H2O2 as an oxidant under… read more here.
Keywords: acylimidazo pyridines; oxidative amination; neat condition; intramolecular oxidative ... See more keywords
Convenient Synthesis of Oxazolo[5,4-h]pyrrolo[4,3,2-de]quinolones via Hypervalent Iodine Mediated Intramolecular Oxidative Cyclization
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DOI: 10.1055/s-0036-1588498
Abstract: A convenient and practical method has been developed for the synthesis of substituted oxazolo[5,4- h ]pyrrolo[4,3,2- de ]quinolones via the intramolecular oxidative cyclization by using PIFA as oxidant and TMSOTf as additive in DCE under… read more here.
Keywords: intramolecular oxidative; oxazolo pyrrolo; convenient synthesis; synthesis ... See more keywords
Iron-Promoted Construction of Indoles via Intramolecular Oxidative C–N Coupling of 2-Alkenylanilines Using Persulfate
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DOI: 10.1055/s-0037-1611521
Abstract: Indole scaffold synthesis relies primarily on oxidative C–H amination of N-protected alkenylanilines for C–N intramolecular cyclization reactions. Herein, for the first time, without N-protection, various readily prepared 2-alkenylanilines were transformed into the desired indole products… read more here.
Keywords: iron promoted; construction indoles; via intramolecular; indoles via ... See more keywords
N-Iodosuccinimide mediated intramolecular oxidative C(sp 2)-S bond formation for the synthesis of 2-aminobenzothiazole derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Sulfur Chemistry"
DOI: 10.1080/17415993.2021.1989436
Abstract: An extremely efficient synthetic method for the preparation of 2-aminobenzothiazole derivatives starting from arylthioureas by using N-iodosuccinimide has been reported. This protocol features a mild reaction conditions, a short reaction time, and metal-free oxidative conditions… read more here.
Keywords: intramolecular oxidative; iodosuccinimide mediated; bond; mediated intramolecular ... See more keywords