C-H Fluoroalkylsulfinylation/Intramolecular Rearrangement for Precise Synthesis of Fluoroalkyl Sulfoxides.
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DOI: 10.1021/acs.orglett.2c01151
Abstract: An efficient methodology to access various fluoroalkyl sulfoxides bearing ortho/para-functionalized amine scaffolds from arylhydroxylamines is described. The transformation was featured with new electrophilic trifluoromethylthiolated reagents, good functional group tolerance, and late-stage modification of complex bioactive… read more here.
Keywords: fluoroalkyl; fluoroalkyl sulfoxides; fluoroalkylsulfinylation intramolecular; intramolecular rearrangement ... See more keywords
Highly Regio- and Stereoselective Intramolecular Rearrangement of Glycidol Acetal to Alkoxy Cyclic Acetals.
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DOI: 10.1021/acs.orglett.2c02397
Abstract: A new class of highly regio- and stereoselective intramolecular rearrangements of glycidol acetals to produce alkoxylated 1,3-dioxolane/1,3-dioxane is demonstrated. Selective Lewis acid activation of acetal generates an oxocarbenium ion that initiates the epoxide ring-opening event,… read more here.
Keywords: intramolecular rearrangement; rearrangement glycidol; glycidol acetal; regio stereoselective ... See more keywords
Synthesis of (2-Aminophenyl)(naphthalen-2-yl)methanones via Intramolecular Rearrangement of (E)-3-Styrylquinolin-4(1H)-ones under Irradiation with 365 nm UV Light
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DOI: 10.1055/s-0037-1610176
Abstract: A highly efficient and environmentally friendly synthesis of (2-aminophenyl)(naphthalen-2-yl)methanones was developed. The (2-aminophenyl)(naphthalen-2-yl)methanone derivatives were obtained in high yields (up to 96%) by the irradiation of ( E )-3-styrylquinolin-4(1 H )-ones in EtOH–H 2 O… read more here.
Keywords: naphthalen methanones; synthesis aminophenyl; styrylquinolin ones; intramolecular rearrangement ... See more keywords