Irinotecan-loaded double-reversible thermogel with improved antitumor efficacy without initial burst effect and toxicity for intramuscular administration.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.03.007
Abstract: Intramuscularly administered, anti-tumour drugs induce severe side effects due to their direct contact with body tissues and initial burst effect. In this study, to solve this problem, a novel double-reversible thermogel system (DRTG) for the… read more here.
Keywords: irinotecan loaded; intramuscular administration; burst effect; initial burst ... See more keywords
Comparative pharmacokinetics of meloxicam oil suspension in pigs at different dosages following intramuscular administration.
Sign Up to like & getrecommendations! Published in 2021 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2021.07.017
Abstract: This study aimed to evaluate the preliminary safety of self-developed meloxicam (MEL) oil suspension and determine the comparative pharmacokinetics of it at 0.8 and 2mg/kg body weight (b.w.) dosages in pigs following a single intramuscular… read more here.
Keywords: intramuscular administration; oil suspension; mel oil; oil ... See more keywords
Pharmacokinetics and pharmacodynamics of hydromorphone after intravenous and intramuscular administration in horses.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary anaesthesia and analgesia"
DOI: 10.1016/j.vaa.2019.08.049
Abstract: OBJECTIVE To compare the pharmacokinetics and pharmacodynamics of hydromorphone in horses after intravenous (IV) and intramuscular (IM) administration. STUDY DESIGN Randomized, masked, crossover design. ANIMALS A total of six adult horses weighing [mean ± standard… read more here.
Keywords: administration; hydromorphone intravenous; intramuscular administration; pharmacodynamics hydromorphone ... See more keywords
Intramuscular administration of autologous total immunoglobulin G induces immunomodulatory effects on T cells in healthy human subjects
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029486
Abstract: Abstract Background: We hypothesized that intramuscular administration of autologous total immunoglobulin G (IgG) could induce an immunomodulatory effect in human subjects. In our previous studies, we showed that intramuscular administration of autologous total IgG could… read more here.
Keywords: administration autologous; autologous total; human subjects; intramuscular administration ... See more keywords
Pharmacokinetics and relative bioavailability of meloxicam oil suspension in pigs after intramuscular administration.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12826
Abstract: This study aimed to develop one novel meloxicam (MEL) oil suspension for sustained-release and compare the pharmacokinetic characteristics of it with MEL conventional formulation in pigs after a single intramuscular administration. Six healthy pigs were… read more here.
Keywords: intramuscular administration; oil suspension; mel oil; oil ... See more keywords
Plasma disposition of florfenicol after intramuscular administration in rabbits pretreated with pentoxifylline.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.13117
Abstract: This work aimed to assess the effects of the coadministration of pentoxifylline (PTX) on the pharmacokinetic profile of florfenicol (FFC) after intramuscular administration in rabbits. Ten New Zealand white rabbits, 1 year of age and 3.9 ± 0.1 kg… read more here.
Keywords: ffc; plasma disposition; administration; florfenicol ... See more keywords
The pharmacokinetics of buserelin after intramuscular administration in pigs and cows
Sign Up to like & getrecommendations! Published in 2022 at "BMC Veterinary Research"
DOI: 10.1186/s12917-022-03237-0
Abstract: Background Buserelin is a luteinizing hormone releasing hormone (LHRH) agonist used for the treatment of hormone-dependent diseases in males and females. However, the pharmacokinetics of buserelin in pigs and cows are not fully understood. This… read more here.
Keywords: administration; pharmacokinetics buserelin; administration pigs; intramuscular administration ... See more keywords
Pharmacokinetics and Pharmacodynamics of Florfenicol in Plasma and Synovial Fluid of Pigs at a Dose of 30 mg/kgbw Following Intramuscular Administration
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12040758
Abstract: A major problem of our time is the ever-increasing resistance to antimicrobial agents in bacterial populations. One of the most effective ways to prevent these problems is to target antibacterial therapies for specific diseases. In… read more here.
Keywords: plasma synovial; mic values; fluid; intramuscular administration ... See more keywords