Factors affecting adherence to intranasal treatment for allergic rhinitis: A qualitative study
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.986
Abstract: To determine the facilitators of and barriers to adherence to use of intranasal pharmacotherapy (daily intranasal corticosteroids and/or antihistamine, and nasal saline irrigation [NSI]), for allergic rhinitis (AR). read more here.
Keywords: factors affecting; allergic rhinitis; affecting adherence; adherence intranasal ... See more keywords
A Feasibility Trial of Home Administration of Intranasal Vaccine by Parents to Eligible Children.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2016.11.018
Abstract: PURPOSE Intranasal vaccines are being developed for protection against many different infectious agents. The currently available intranasal live attenuated influenza vaccine (LAIV) is only approved for administration by medical personnel. We conducted a pilot study… read more here.
Keywords: laiv; administration; intranasal; home administration ... See more keywords
Nose-to-brain delivery of levetiracetam after intranasal administration to mice.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.047
Abstract: Despite being one of the most commonly prescribed antiepileptic drugs, levetiracetam is marketed in oral and intravenous dosage forms, which are associated to drug-drug interactions and drug-resistant epilepsy (DRE). The purpose of the present study… read more here.
Keywords: intranasal; levetiracetam; drug; intranasal administration ... See more keywords
10 Pharmacodynamics and Tolerability of Intranasally Administered Immediate-Release Amphetamine Sulfate Among Recreational Intranasal StimulantUsers
Sign Up to like & getrecommendations! Published in 2019 at "CNS Spectrums"
DOI: 10.1017/s1092852919000063
Abstract: Abstract Study Objective Despite increased nonmedical use of ADHD prescription stimulants, there are limited data to inform selection of intranasal doses for abuse-potential evaluations. This study determined a dose of amphetamine sulfate that is tolerable… read more here.
Keywords: intranasal; amphetamine sulfate; drug liking; placebo ... See more keywords
LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-51356-w
Abstract: Enterotoxin-based adjuvants including cholera toxin and heat-labile toxin (LT) are powerful manipulators of mucosal immunity; however, past clinical trials identified unacceptable neurological toxicity when LT or mutant AB5 adjuvant proteins were added to intranasal vaccines.… read more here.
Keywords: protection; intranasal; adjuvant improves; enterotoxin ... See more keywords
Intranasal Osteosarcoma in a Dog-A Case Report.
Sign Up to like & getrecommendations! Published in 2018 at "Topics in companion animal medicine"
DOI: 10.1053/j.tcam.2018.04.001
Abstract: Osteosarcoma is the most commonly reported bone tumor in dogs, typically affecting the axial and appendicular skeleton. Involvement of the paranasal sinuses and the nasal cavity is extremely rare. This report describes a 6-year-old, female,… read more here.
Keywords: intranasal; dog case; report; intranasal osteosarcoma ... See more keywords
Intranasal spray of cubosomal Tizanidine Hydrochloride for brain targeting: In-vitro and in-vivo characterization.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of microencapsulation"
DOI: 10.1080/02652048.2023.2209651
Abstract: Tizanidine HCl (TH) is used as first-line therapy for the treatment of muscular spasm. The intranasal cubosomal delivery system of TH for site-specific delivery i.e. CNS was developed. Cubosomes of TH were prepared using Glyceryl… read more here.
Keywords: intranasal spray; vivo; brain; spray cubosomal ... See more keywords
Developments in the discovery and design of intranasal antidepressants
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2020.1776697
Abstract: ABSTRACT Introduction Depression remains a major cause of morbidity worldwide; consequently, there is a need in neuropsychiatry for new antidepressants with a rapid onset of action. Intranasal administration of antidepressants is an attractive and promising… read more here.
Keywords: discovery design; design intranasal; intranasal; intranasal antidepressants ... See more keywords
Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I.
Sign Up to like & getrecommendations! Published in 2017 at "Human gene therapy"
DOI: 10.1089/hum.2017.187
Abstract: Mucopolysaccharidosis type I (MPS I) is a progressive, multi-systemic, inherited metabolic disease caused by deficiency of α-L-iduronidase (IDUA). Current treatments for this disease are ineffective in treating central nervous system (CNS) disease due to the… read more here.
Keywords: mucopolysaccharidosis type; intranasal; central nervous; disease ... See more keywords
Mixed support for a causal link between single dose intranasal oxytocin and spiritual experiences: opposing effects depending on individual proclivities for absorption
Sign Up to like & getrecommendations! Published in 2018 at "Social Cognitive and Affective Neuroscience"
DOI: 10.1093/scan/nsy068
Abstract: Abstract Intranasal oxytocin (OT) has previously been found to increase spirituality, an effect moderated by OT‐related genotypes. This pre‐registered study sought to conceptually replicate and extend those findings. Using a single dose of intranasal OT… read more here.
Keywords: absorption; intranasal; treatment; intranasal oxytocin ... See more keywords
Intranasal lidocaine for acute migraine
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015699
Abstract: Background: Intranasal lidocaine has been shown to be effective in treating patients with acute migraines; however, its efficacy is still controversial. The aim of our study is to assess the efficacy and safety of intranasal… read more here.
Keywords: medicine; lidocaine acute; intranasal; intranasal lidocaine ... See more keywords