Intranasal dexmedetomidine in elderly subjects with or without beta blockade: a randomised double-blind single-ascending-dose cohort study.
Sign Up to like & getrecommendations! Published in 2020 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2019.12.025
Abstract: BACKGROUND The aim of this double-blind, placebo-controlled, single-ascending-dose study was to determine the safety and tolerability of intranasal dexmedetomidine in the elderly. METHODS We randomly assigned 48 surgical patients ≥65 yr of age to receive… read more here.
Keywords: double blind; intranasal dexmedetomidine; dexmedetomidine elderly; single ascending ... See more keywords
Intranasal dexmedetomidine for transthoracic echocardiography in infants with shunt-dependent single ventricle heart disease.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951122002074
Abstract: OBJECTIVES We investigated the efficacy and complication profile of intranasal dexmedetomidine for transthoracic echocardiography sedation in patients with single ventricle physiology and shunt-dependent pulmonary blood flow during the high-risk interstage period. METHODS A single-centre, retrospective… read more here.
Keywords: single ventricle; echocardiography; shunt dependent; intranasal dexmedetomidine ... See more keywords
Fifty Percent Effective Dose of Intranasal Dexmedetomidine Sedation for Transthoracic Echocardiography in Children With Cyanotic and Acyanotic Congenital Heart Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2019.11.037
Abstract: OBJECTIVES To determine the 50% and 95% effective dose of intranasal dexmedetomidine sedation for transthoracic echocardiography in children with cyanotic and acyanotic congenital heart disease. DESIGN A prospective, nonrandomized study. SETTING A tertiary care teaching… read more here.
Keywords: transthoracic echocardiography; intranasal dexmedetomidine; dexmedetomidine sedation; sedation transthoracic ... See more keywords
Novel Use of Intranasal Dexmedetomidine for Refractory Irritability in Pediatric Home Care.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of palliative medicine"
DOI: 10.1089/jpm.2022.0420
Abstract: Background: Dexmedetomidine is a selective alpha-2 agonist with sedative, analgesic, and anxiolytic properties used intravenously for procedural sedation and in the intensive care unit. The reported use of intranasal (IN) dexmedetomidine for symptom management in… read more here.
Keywords: use intranasal; refractory irritability; intranasal dexmedetomidine; care ... See more keywords
Atomised intranasal dexmedetomidine versus oral melatonin in prevention of emergence delirium in children undergoing ophthalmic surgery with sevoflurane
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001727
Abstract: BACKGROUND Melatonin and dexmedetomidine have both been used as a premedication to decrease emergence delirium in children. The effectiveness of oral melatonin, compared with atomised intranasal dexmedetomidine, in this role is not well studied. OBJECTIVE… read more here.
Keywords: emergence delirium; intranasal dexmedetomidine; oral melatonin; melatonin ... See more keywords
Intranasal dexmedetomidine sedation for paediatric MRI by radiology personnel
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001786
Abstract: BACKGROUND MRI often requires sedation or anaesthesia to ensure good image quality in paediatric patients. Access to paediatric anaesthesia services is, however, a limiting factor for effective paediatric MRI service, and alternative sedation methods are,… read more here.
Keywords: radiology; intranasal dexmedetomidine; rate; mri ... See more keywords
The 90% effective dose of intranasal dexmedetomidine for procedural sedation in children with congenital heart disease before and after surgery: A biased‐coin design up‐and‐down sequential allocation trial
Sign Up to like & getrecommendations! Published in 2020 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13693
Abstract: Intranasal dexmedetomidine can provide adequate sedation during short procedures. However, there are few reports investigating the effective dose of intranasal dexmedetomidine for sedation in children with congenital heart disease (CHD) before and after surgery. read more here.
Keywords: sedation children; dose intranasal; intranasal dexmedetomidine; children congenital ... See more keywords
A randomised controlled trial of oral chloral hydrate vs. intranasal dexmedetomidine before computerised tomography in children
Sign Up to like & getrecommendations! Published in 2017 at "Anaesthesia"
DOI: 10.1111/anae.13981
Abstract: Chloral hydrate is commonly used to sedate children for painless procedures. Children may recover more quickly after sedation with dexmedetomidine, which has a shorter half‐life. We randomly allocated 196 children to chloral hydrate syrup 50… read more here.
Keywords: intranasal dexmedetomidine; syrup; hydrate; chloral hydrate ... See more keywords
Dexmedetomidine improves success of paediatric MRI sedation
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2021-322734
Abstract: Objective To improve success rates of children requiring sedation for MRI. Methods Audits of sedation success for children attending planned MRI using three different approaches: (1) National Institute for Health and Care Excellence (NICE) guidance… read more here.
Keywords: success; chloral hydrate; intranasal dexmedetomidine; mri ... See more keywords
Efficacy and safety of intranasal dexmedetomidine versus oral chloral hydrate as sedatives for pediatric patients: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2021-002038
Abstract: This study was designed to review published literature to determine the efficacy and safety of intranasal dexmedetomidine versus oral chloral hydrate (CH) for sedation in pediatric patients based on qualified studies. We searched the PubMed,… read more here.
Keywords: efficacy safety; intranasal dexmedetomidine; sedation; pediatric patients ... See more keywords
Spontaneous Conversions of Supraventricular Tachycardia to Sinus Rhythm in Children After Premedication With Intranasal Dexmedetomidine: A Case Report.
Sign Up to like & getrecommendations! Published in 2018 at "A&A Practice"
DOI: 10.1213/xaa.0000000000000786
Abstract: Intranasal dexmedetomidine administered as premedication before anesthesia and cardioversion appears to have the potential to facilitate the return of sinus rhythm. Two children, 3.5 and 1.5 years old, with recurrent supraventricular tachycardia in need of… read more here.
Keywords: intranasal dexmedetomidine; supraventricular tachycardia; sinus rhythm; premedication ... See more keywords