Buspirone maintenance does not alter the reinforcing, subjective, and cardiovascular effects of intranasal methamphetamine.
Sign Up to like & getrecommendations! Published in 2017 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2017.08.038
Abstract: BACKGROUND Medications development efforts for methamphetamine-use disorder have targeted central monoamines because these systems are directly involved in the effects of methamphetamine. Buspirone is a dopamine autoreceptor and D3 receptor antagonist and partial agonist at… read more here.
Keywords: methamphetamine use; intranasal methamphetamine; maintenance; buspirone maintenance ... See more keywords
The effects of acute oral naltrexone pretreatment on the abuse potential of intranasal methamphetamine, and the relationship between reward/punishment sensitivity and methamphetamine’s effects
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000671
Abstract: One potential medication for treating methamphetamine use disorder is the opioid antagonist naltrexone (NLTX). Despite encouraging preclinical findings, the results of clinical studies have been mixed. The primary aim of the current trial was to… read more here.
Keywords: pretreatment; sensitivity; reward punishment; methamphetamine ... See more keywords