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   Articles with "intranasal npy" as a keyword



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Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease

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recommendations! Published in 2018 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2018.01.001

Abstract: ABSTRACT Huntington's disease (HD) is a monogenic inherited polyglutamine‐mediated neurodegenerative disorder for which effective therapies are currently unavailable. Neuropeptide Y (NPY) has been implicated as a potential therapeutic target in several neurodegenerative diseases, including HD.… read more here.

Keywords: intranasal npy; npy npy13; pathology; activation ... See more keywords
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Potential benefits of intranasal neuropeptide Y include sustained extinction of fear memory.

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recommendations! Published in 2023 at "Journal of neuroendocrinology"

DOI: 10.1111/jne.13279

Abstract: Compelling evidence in animals and humans from a variety of approaches demonstrate that neuropeptide Y (NPY) in the brain can provide resilience to development of many stress-elicited symptoms. Preclinical experiments demonstrated that delivery of NPY… read more here.

Keywords: stress; extinction; intranasal npy; benefits intranasal ... See more keywords