Intranasal Spray Formulation Containing Rizatriptan benzoate for the Treatment of Migraine.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118702
Abstract: Rizatriptan produces antimigraine activity by acting as selective agonist of 5-HT1B and 5-HT1D receptors present on intracranial and extracerebral blood vessels. Absorption from oral tablet is slow with Tmax of approximately 1-1.5 hours. A few… read more here.
Keywords: rizatriptan benzoate; formulation; intranasal spray; formulation containing ... See more keywords
Intranasal spray of cubosomal Tizanidine Hydrochloride for brain targeting: In-vitro and in-vivo characterization.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of microencapsulation"
DOI: 10.1080/02652048.2023.2209651
Abstract: Tizanidine HCl (TH) is used as first-line therapy for the treatment of muscular spasm. The intranasal cubosomal delivery system of TH for site-specific delivery i.e. CNS was developed. Cubosomes of TH were prepared using Glyceryl… read more here.
Keywords: intranasal spray; vivo; brain; spray cubosomal ... See more keywords