Factors Limiting the Translatability of Rodent Model–Based Intranasal Vaccine Research to Humans
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DOI: 10.1208/s12249-022-02330-9
Abstract: The intranasal route of vaccination presents an attractive alternative to parenteral routes and offers numerous advantages, such as the induction of both mucosal and systemic immunity, needle-free delivery, and increased patient compliance. Despite demonstrating promising… read more here.
Keywords: intranasal vaccine; based intranasal; translatability rodent; vaccine research ... See more keywords
Evaluation of Efficacy of Surface Coated versus Encapsulated Influenza Antigens in Mannose–Chitosan Nanoparticle-Based Intranasal Vaccine in Swine
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DOI: 10.3390/vaccines12060647
Abstract: This study focuses on the development and characterization of an intranasal vaccine platform using adjuvanted nanoparticulate delivery of swine influenza A virus (SwIAV). The vaccine employed whole inactivated H1N2 SwIAV as an antigen and STING-agonist… read more here.
Keywords: mannose chitosan; intranasal vaccine; surface; swine ... See more keywords