Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node
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DOI: 10.1038/s41467-019-14039-8
Abstract: Mechanisms for human sinoatrial node (SAN) dysfunction are poorly understood and whether human SAN excitability requires voltage-gated sodium channels (Nav) remains controversial. Here, we report that neuronal (n)Nav blockade and selective nNav1.6 blockade during high-resolution… read more here.
Keywords: sinoatrial node; sodium channels; intranodal conduction; human sinoatrial ... See more keywords