Successful treatment of metastatic congenital intraocular medulloepithelioma with neoadjuvant chemotherapy, enucleation and superficial parotidectomy
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2018.06.019
Abstract: Purpose To report a case of metastatic intraocular medulloepithelioma successfully treated with neoadjuvant chemotherapy, superficial parotidectomy, and enucleation. Observations A 5-year-old male with history of cataract surgery, glaucoma drainage device, endocyclophotocoagulation, scleral patch grafting, and… read more here.
Keywords: chemotherapy; intraocular medulloepithelioma; medulloepithelioma; neoadjuvant chemotherapy ... See more keywords
Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma
Sign Up to like & getrecommendations! Published in 2021 at "Oncogenesis"
DOI: 10.1038/s41389-021-00369-0
Abstract: Intraocular medulloepithelioma (IO-MEPL) is a rare embryonal ocular neoplasm, prevalently occurring in children. IO-MEPLs share histomorphological features with CNS embryonal tumors with multilayered rosettes (ETMRs), referred to as intracranial medulloepitheliomas. While Sonic hedgehog (SHH) and… read more here.
Keywords: wnt signaling; wnt; intraocular medulloepithelioma; sonic hedgehog ... See more keywords
Intraocular medulloepithelioma clinical features and management of 11 cases
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DOI: 10.1136/bjo-2022-322449
Abstract: Aims To describe the clinical features, imaging characteristics, histopathology, treatment and outcomes of intraocular medulloepithelioma. Methods Medical records of 11 patients with clinically or histopathologically confirmed medulloepithelioma were retrieved and reviewed. Clinical features, diagnostic challenges,… read more here.
Keywords: medulloepithelioma clinical; intraocular medulloepithelioma; management; medulloepithelioma ... See more keywords
Intraocular medulloepithelioma – A review of clinical features, DICER 1 mutation, and management
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_845_19
Abstract: Intraocular medulloepithelioma is a nonhereditary neoplasm of childhood arising from primitive medullary epithelium. It most often involves the ciliary body. Most patients present between 2 and 10 years of age with loss of vision, pain,… read more here.
Keywords: intraocular medulloepithelioma; features dicer; medulloepithelioma review; clinical features ... See more keywords