Long‐term observation of pulmonary toxicity of toner with external additives following a single intratracheal instillation in rats
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DOI: 10.1002/1348-9585.12146
Abstract: Along with technological innovations for improving the efficiency of printing, nanoparticles have been added to the surface of toners, and there is concern about the harmful effects of those components. We investigated, through a long‐term… read more here.
Keywords: long term; external additives; intratracheal instillation; toner external ... See more keywords
Pulmonary toxicity of tungsten trioxide nanoparticles in an inhalation study and an intratracheal instillation study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Occupational Health"
DOI: 10.1002/1348-9585.12367
Abstract: We conducted inhalation and intratracheal instillation studies in order to examine the effects of tungsten trioxide (WO3) nanoparticles on the lung, and evaluated whether or not the nanoparticles would cause persistent lung inflammation. read more here.
Keywords: intratracheal instillation; tungsten trioxide; pulmonary toxicity; inhalation ... See more keywords
Time‐course analysis of pulmonary inflammation induced by intratracheal instillation of nanosized crystalline silica particles in F344 rats
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DOI: 10.1002/jat.4411
Abstract: Crystalline silica is an important cause of serious pulmonary diseases, and its toxic potential is known to be associated with its surface electrical properties. However, in vivo data clarifying the relevance of silica's toxic potential,… read more here.
Keywords: inflammation; spb; intratracheal instillation; crystalline ... See more keywords
iTRAQ-Based Proteomic Profiling of Potential Biomarkers in Rat Serum for Uranium Tailing Suspension Intratracheal Instillation.
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DOI: 10.1021/acs.jproteome.0c00766
Abstract: Protection against low-dose ionizing radiation is of great significance. Uranium tailings are formed as a byproduct of uranium mining and a potential risk to organisms. In this study, we identified potential biomarkers associated with exposure… read more here.
Keywords: potential biomarkers; uranium tailing; low dose; intratracheal instillation ... See more keywords
Effects of administering different vehicles via single intratracheal instillation on responses in the lung and pleural cavity of Crl:CD(SD) rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2019-0060
Abstract: Intratracheal instillation is the introduction of a substance directly into the trachea. Intratracheal instillation has been used to investigate the lung toxicity of several chemicals and requires the suspension or dissolution of test material in… read more here.
Keywords: single intratracheal; different vehicles; crl rats; intratracheal instillation ... See more keywords
Comparison of acute inhalation toxicity of sulfuric acid by the inhalation and intratracheal instillation methods
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DOI: 10.1293/tox.2020-0086
Abstract: Recently, intratracheal instillation has been focused on as a simple, low-cost alternative to the inhalation method. In this study, intratracheal instillation of sulfuric acid, a typical acidic compound, was performed to compare the acute toxicity… read more here.
Keywords: intratracheal instillation; sulfuric acid; toxicity; inhalation ... See more keywords
Acute Toxicity in the Rat Lung Induced by Intratracheal Instillation of Glycolic Acid
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DOI: 10.21873/invivo.12883
Abstract: Background/Aim: Inhalation toxicity tests of glycolic acid, which is used in many household products, have been reported, but the pulmonary toxicity of glycolic-acid has not been confirmed. Here, the lung damage caused by glycolic acid… read more here.
Keywords: glycolic acid; instillation glycolic; toxicity; intratracheal instillation ... See more keywords