Intratumoral Anti-PD-1 Nanoformulation Improves Its Biodistribution.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c22479
Abstract: Intratumoral administration of immune checkpoint inhibitors, such as programmed cell death-1 antibodies (aPD-1), is a promising approach toward addressing both the low patients' responses and high off-target toxicity, but good preclinical results have not translated… read more here.
Keywords: free apd; intratumoral administration; intratumoral anti; apd ... See more keywords
Survival of subjects with recurrent glioblastoma receiving intratumoral administration of controlled IL-12 with limited exposure to dexamethasone.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.2564
Abstract: 2564Background: Interleukin-12 (IL-12) results in anti-tumor responses in preclinical models but requires tightly controlled production to achieve safety and elicit immune system activation to real... read more here.
Keywords: survival subjects; glioblastoma receiving; receiving intratumoral; subjects recurrent ... See more keywords