Intratumoral CD8+ T cells as a potential positive predictor of chemoimmunotherapy response in PD-L1-negative advanced gastric cancer patients: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-644
Abstract: Background Previous studies have shown that PD-L1-positive advanced gastric cancer (GC) patients could achieve clinical benefit after receiving immune checkpoint inhibitors (ICI) in initial or subsequent therapy. A number of prospective studies such as Keynote-158… read more here.
Keywords: chemoimmunotherapy; cohort; intratumoral cd8; response ... See more keywords
Digital Quantification of Intratumoral CD8+ T-Cells Predicts Relapse and Unfavorable Outcome in Uveal Melanoma
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DOI: 10.3390/cancers14235959
Abstract: Simple Summary In this study, we used digital pathology and image analysis for the prediction of the prognosis in uveal melanoma (UM). We retrospectively evaluated a total of 404 histopathological slides of 101 patients. Immune… read more here.
Keywords: uveal melanoma; pathology; intratumoral cd8; image ... See more keywords
Prognostic Role of Tumoral PD-L1 and IDO1 Expression, and Intratumoral CD8+ and FoxP3+ Lymphocyte Infiltrates in 132 Primary Cutaneous Merkel Cell Carcinomas
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DOI: 10.3390/ijms22115489
Abstract: The association of immune markers and clinicopathologic features and patient outcome has not been extensively studied in Merkel cell carcinoma (MCC). We correlated tumoral PD-L1 and IDO1 expression, and intratumoral CD8+ and FoxP3+ lymphocytes count… read more here.
Keywords: intratumoral cd8; merkel cell; expression; cd8 foxp3 ... See more keywords