Articles with "intratumoral microbiota" as a keyword



Association of Intratumoral Microbiota With Prognosis in Patients With Nasopharyngeal Carcinoma From 2 Hospitals in China

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Published in 2022 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2022.2810

Abstract: Key Points Question Is there characteristic microbiota in nasopharyngeal carcinoma (NPC) tissues and, if so, is it associated with prognosis? Findings In this multicenter cohort study including 802 patients with NPC, we confirmed the existence… read more here.

Keywords: nasopharyngeal carcinoma; prognosis; microbiota; intratumoral microbiota ... See more keywords

The value of intratumoral microbiota in the diagnosis and prognosis of tumors

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Published in 2024 at "Cell Biochemistry and Function"

DOI: 10.1002/cbf.3999

Abstract: Intratumoral microbiota (ITM) are microorganisms present in tumor cells. ITM participate in tumor development by affecting tumor cells directly and the tumor microenvironment (TME), indirectly. Alterations in ITM instigate changes in tumor DNA, activate oncogenic… read more here.

Keywords: diagnosis prognosis; intratumoral microbiota; prognosis; value intratumoral ... See more keywords

Hepatitis B virus‐related hepatocellular carcinoma exhibits distinct intratumoral microbiota and immune microenvironment signatures

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Published in 2024 at "Journal of Medical Virology"

DOI: 10.1002/jmv.29485

Abstract: Emerging evidence supports a high prevalence of cancer type‐specific microbiota residing within tumor tissues. The intratumoral microbiome in hepatocellular carcinoma (HCC), especially in viral (hepatitis B virus [HBV]/hepatitis C virus [HCV]) HCC, has not been… read more here.

Keywords: hepatitis virus; hcc; intratumoral microbiota; tumor ... See more keywords

A Nano-Strategy for Advanced Triple-Negative Breast Cancer Therapy by Regulating Intratumoral Microbiota.

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Published in 2025 at "Nano letters"

DOI: 10.1021/acs.nanolett.5c00298

Abstract: Intratumoral microbiota have been identified as a component of the tumor microenvironment that regulates the metastatic behavior of tumors. They serve not only as indicators of tumor pathology but also as potential drug targets in… read more here.

Keywords: cancer; intratumoral microbiota; negative breast; triple negative ... See more keywords

The intratumoral microbiota in breast cancer: from basic research to clinical translation

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Published in 2025 at "Gut Microbes"

DOI: 10.1080/19490976.2025.2560695

Abstract: ABSTRACT Breast cancer remains a leading global malignancy among women, with increasing incidence and mortality. Recent advances in multi-omics technologies have revealed the presence of diverse microbial communities in the tumor microenvironment, comprising bacteria, viruses,… read more here.

Keywords: microbiota breast; breast cancer; intratumoral microbiota; microbiota ... See more keywords

Intratumoral microbiota: New Frontiers in Tumor Immunity.

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Published in 2022 at "Carcinogenesis"

DOI: 10.1093/carcin/bgac063

Abstract: Microbiota-host interactions are a hot topic of research because of their important role in regulating the malignant transformation of cancer cells and cancer-related immunity. The role of gut microbiota, oral microbiota, and skin microbiota in… read more here.

Keywords: microbiota new; new frontiers; intratumoral microbiota; microbiota ... See more keywords

Intratumoral Microbiota: Unraveling their Oncogenic Impact on Cancer Progression With Focus on Breast Cancer Therapeutic Outcomes

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Published in 2024 at "AntiCancer Research"

DOI: 10.21873/anticanres.17035

Abstract: The gut microbiota has been implicated in many cancers through the secretion of blood-traveling metabolites or activation of oncogenic signaling. Currently, specific microbial signatures have been detected in the human breast, which are different from… read more here.

Keywords: cancer; breast cancer; breast; progression ... See more keywords

The intratumoral microbiota: a new horizon in cancer immunology

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Published in 2024 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2024.1409464

Abstract: Over the past decade, advancements in high-throughput sequencing technologies have led to a qualitative leap in our understanding of the role of the microbiota in human diseases, particularly in oncology. Despite the low biomass of… read more here.

Keywords: cancer; immunology; tumor immune; intratumoral microbiota ... See more keywords

Research progress on the impact of intratumoral microbiota on the immune microenvironment of malignant tumors and its role in immunotherapy

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Published in 2024 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2024.1389446

Abstract: Microbiota has been closely related to human beings, whose role in tumor development has also been widely investigated. However, previous studies have mainly focused on the gut, oral, and/or skin microbiota. In recent years, the… read more here.

Keywords: role; microbiota; intratumoral microbiota; microbiota immune ... See more keywords

Intratumoral microbiota: implications for cancer progression and treatment

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Published in 2025 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2025.1551515

Abstract: The human body has a diverse range of microbiota that influences human physiological processes and alters disease risk, involving cancer. Metagenomic sequencing investigations have revealed that the microbiota is an element of the tumor microenvironment,… read more here.

Keywords: cancer; treatment; progression; intratumoral microbiota ... See more keywords